Decarboxylation is the loss of ____ from the carboxyl group of an acid Most carboxylic acids are quite resistant to moderate heat. Exceptions are carboxylic acids that have a carbonyl group __ to the carbonyl These carboxylic acids are derived from Claisen condensations (following ester hydrolysis). CO 2 β
The decarboxylative cyanation reaction, as a degrdn.-reconstruction approach, is esp. useful in rapid carboxylic acid carbon isotope labeling, however development toward its application as a widespread technique has stalled at the early stages due to numerous limitations which include somewhat narrow applicability.